2cas

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[[Image:2cas.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_2cas| PDB=2cas | SCENE= }}
{{STRUCTURE_2cas| PDB=2cas | SCENE= }}
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'''THE CANINE PARVOVIRUS EMPTY CAPSID STRUCTURE'''
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===THE CANINE PARVOVIRUS EMPTY CAPSID STRUCTURE===
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==Overview==
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The structure of empty canine parvovirus capsids shows that residues 37 to the carboxy-terminal residue 584 (VP2 numbering) are ordered in each of the 60 subunits. The central structural motif of each subunit is the eight-stranded antiparallel beta-barrel that has been found in many other virus structures. Five beta-hairpin turns form a beta-cylindrical structure at each icosahedral 5-fold axis. The N-terminal glycine-rich sequence can be accommodated within this cylinder without excessive steric hindrance, consistent with the electron density distribution. By far the largest conformational differences between the full and empty virus were found in the region where some ordered DNA has been observed to bind in canine parvovirus full particles. Extensive interactions among 3-fold related subunits indicate that a trimeric subunit might be a viral assembly intermediate.
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The line below this paragraph, {{ABSTRACT_PUBMED_8377200}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8377200 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8377200}}
==About this Structure==
==About this Structure==
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[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]
[[Category: Parvovirus coat protein]]
[[Category: Parvovirus coat protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:36:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:10:32 2008''

Revision as of 05:10, 29 July 2008

Image:2cas.png

Template:STRUCTURE 2cas

THE CANINE PARVOVIRUS EMPTY CAPSID STRUCTURE

Template:ABSTRACT PUBMED 8377200

About this Structure

2CAS is a Single protein structure of sequence from Canine parvovirus. Full crystallographic information is available from OCA.

Reference

The canine parvovirus empty capsid structure., Wu H, Rossmann MG, J Mol Biol. 1993 Sep 20;233(2):231-44. PMID:8377200

Page seeded by OCA on Tue Jul 29 08:10:32 2008

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