This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2gop

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2gop.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2gop.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2gop| PDB=2gop | SCENE= }}
{{STRUCTURE_2gop| PDB=2gop | SCENE= }}
-
'''The beta-propeller domain of the Trilobed protease from Pyrococcus furiosus reveals an open velcro topology'''
+
===The beta-propeller domain of the Trilobed protease from Pyrococcus furiosus reveals an open velcro topology===
-
==Overview==
+
<!--
-
In the proteolytic pathway of prokaryotic and eukaryotic organisms, proteins tagged for proteolysis are firstly shredded into smaller peptides by compartmentalized proteases such as the proteasome complex. Accordingly, a variety of downstream proteases have evolved to further hydrolyze these peptides to the level of free amino acids. In the search for such downstream proteases, a high-molecular-weight protease complex called trilobed protease (TLP) was recently discovered in the archaeon Pyroccocus furiosus. The crystal structure of the N-terminal beta-propeller domain of the trilobed protease at 2 A resolution shows that the trilobed protease utilizes this accessory domain to control substrate access to the active site. Modelling of the intact TLP monomer suggests that this protease has an additional side entrance to its active site as in the DPP-IV or tricorn protease complexes.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17242511}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17242511 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17242511}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Beta propeller]]
[[Category: Beta propeller]]
[[Category: Open velcro]]
[[Category: Open velcro]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:20:46 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:15:36 2008''

Revision as of 05:15, 29 July 2008

Image:2gop.png

Template:STRUCTURE 2gop

The beta-propeller domain of the Trilobed protease from Pyrococcus furiosus reveals an open velcro topology

Template:ABSTRACT PUBMED 17242511

About this Structure

2GOP is a Single protein structure of sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA.

Reference

The beta-propeller domain of the trilobed protease from Pyrococcus furiosus reveals an open Velcro topology., Bosch J, Tamura T, Tamura N, Baumeister W, Essen LO, Acta Crystallogr D Biol Crystallogr. 2007 Feb;63(Pt 2):179-87. Epub 2007, Jan 16. PMID:17242511

Page seeded by OCA on Tue Jul 29 08:15:36 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gop"
Personal tools