1p9n

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{{STRUCTURE_1p9n| PDB=1p9n | SCENE= }}
{{STRUCTURE_1p9n| PDB=1p9n | SCENE= }}
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'''Crystal structure of Escherichia coli MobB.'''
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===Crystal structure of Escherichia coli MobB.===
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==Overview==
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The crystal structure of Escherichia coli MobB, an enzyme involved in the final step of molybdenum-cofactor biosynthesis, forms intertwined dimers. Each molecule consists of two segments and requires the second monomer for stable folding. Dimerization buries a quarter of the solvent-accessible area of the monomer. These dimers assemble into a hexagonal lattice with P6(4)22 symmetry and occupy only approximately 25% of the unit-cell volume. The symmetry-related dimers associate tightly into a helical structure with a diameter of 250 A and a pitch of 98 A. Two such helices are intertwined, shifted by 49 A along the sixfold axis. Within the crystal, these helices form thin-walled cylinders with an external diameter of 250 A and an internal diameter of 190 A. Their center is filled with solvent. These cylinders pack closely together, forming a hexagonal lattice with the highest possible packing density. This arrangement of dimers allows extensive intermolecular contacts with 75% solvent content in the crystal.
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(as it appears on PubMed at http://www.pubmed.gov), where 14646116 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14646116}}
==About this Structure==
==About this Structure==
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:51:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:22:51 2008''

Revision as of 05:22, 29 July 2008

Image:1p9n.png

Template:STRUCTURE 1p9n

Crystal structure of Escherichia coli MobB.

Template:ABSTRACT PUBMED 14646116

About this Structure

1P9N is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Molecules of Escherichia coli MobB assemble into densely packed hollow cylinders in a crystal lattice with 75% solvent content., Rangarajan SE, Tocilj A, Li Y, Iannuzzi P, Matte A, Cygler M, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2348-52. Epub 2003, Nov 27. PMID:14646116

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