1pdm

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{{STRUCTURE_1pdm| PDB=1pdm | SCENE= }}
{{STRUCTURE_1pdm| PDB=1pdm | SCENE= }}
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'''Fitting of gp8 structure into the cryoEM reconstruction of the bacteriophage T4 baseplate'''
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===Fitting of gp8 structure into the cryoEM reconstruction of the bacteriophage T4 baseplate===
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==Overview==
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The baseplate of bacteriophage T4 is a multiprotein molecular machine that controls host cell recognition, attachment, tail sheath contraction and viral DNA ejection. We report here the three-dimensional structure of the baseplate-tail tube complex determined to a resolution of 12 A by cryoelectron microscopy. The baseplate has a six-fold symmetric, dome-like structure approximately 520 A in diameter and approximately 270 A long, assembled around a central hub. A 940 A-long and 96 A-diameter tail tube, coaxial with the hub, is connected to the top of the baseplate. At the center of the dome is a needle-like structure that was previously identified as a cell puncturing device. We have identified the locations of six proteins with known atomic structures, and established the position and shape of several other baseplate proteins. The baseplate structure suggests a mechanism of baseplate triggering and structural transition during the initial stages of T4 infection.
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{{ABSTRACT_PUBMED_12923574}}
==About this Structure==
==About this Structure==
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[[Category: Rossmann, M G.]]
[[Category: Rossmann, M G.]]
[[Category: Structural protein]]
[[Category: Structural protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:58:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:42:30 2008''

Revision as of 08:42, 29 July 2008

Image:1pdm.png

Template:STRUCTURE 1pdm

Fitting of gp8 structure into the cryoEM reconstruction of the bacteriophage T4 baseplate

Template:ABSTRACT PUBMED 12923574

About this Structure

1PDM is a Single protein structure of sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of bacteriophage T4 baseplate., Kostyuchenko VA, Leiman PG, Chipman PR, Kanamaru S, van Raaij MJ, Arisaka F, Mesyanzhinov VV, Rossmann MG, Nat Struct Biol. 2003 Sep;10(9):688-93. Epub 2003 Aug 17. PMID:12923574

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