This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2nzh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2nzh.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2nzh.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2nzh| PDB=2nzh | SCENE= }}
{{STRUCTURE_2nzh| PDB=2nzh | SCENE= }}
-
'''Crystal structure of a secretion chaperone CsaA from Bacillus subtilis in the space group P 4 21 2'''
+
===Crystal structure of a secretion chaperone CsaA from Bacillus subtilis in the space group P 4 21 2===
-
==Overview==
+
<!--
-
Bacillus subtilis CsaA (BsCsaA) has been proposed to act as a protein-secretion chaperone in the Sec-dependent translocation pathway, possibly compensating for the lack of SecB in the Gram-positive eubacterium Bacillus subtilis. This paper presents the cloning, purification, crystallization and structures of BsCsaA in two space groups (P42(1)2 and P3(2)21) solved and refined to resolutions of 1.9 and 2.0 A, respectively. These structures complement the previously available crystal structure of CsaA from the Gram-negative eubacterium Thermus thermophilus (TtCsaA) and provide a direct structural basis for the interpretation of previously available biochemical data on BsCsaA. The sequence and structure of the proposed substrate-binding pocket are analyzed and discussed. A comparison with the TtCsaA structure reveals a different pattern of electrostatic potential in the vicinity of the binding site, which overlaps with a region of high sequence variability. In addition, the dimerization interface of this homodimeric protein is analyzed and discussed.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17372352}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17372352 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17372352}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Homodimer]]
[[Category: Homodimer]]
[[Category: Oligonucleotide/oligosaccharide binding fold]]
[[Category: Oligonucleotide/oligosaccharide binding fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 10:07:07 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:48:30 2008''

Revision as of 08:48, 29 July 2008

Image:2nzh.png

Template:STRUCTURE 2nzh

Crystal structure of a secretion chaperone CsaA from Bacillus subtilis in the space group P 4 21 2

Template:ABSTRACT PUBMED 17372352

About this Structure

2NZH is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Crystallographic analysis of Bacillus subtilis CsaA., Shapova YA, Paetzel M, Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):478-85. Epub 2007, Mar 16. PMID:17372352

Page seeded by OCA on Tue Jul 29 11:48:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2nzh"
Personal tools