From Proteopedia
(Difference between revisions)
proteopedia linkproteopedia link
|
|
| Line 1: |
Line 1: |
| - | [[Image:2pyr.jpg|left|200px]] | + | {{Seed}} |
| | + | [[Image:2pyr.png|left|200px]] |
| | | | |
| | <!-- | | <!-- |
| Line 9: |
Line 10: |
| | {{STRUCTURE_2pyr| PDB=2pyr | SCENE= }} | | {{STRUCTURE_2pyr| PDB=2pyr | SCENE= }} |
| | | | |
| - | '''PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)'''
| + | ===PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)=== |
| | | | |
| | | | |
| - | ==Overview==
| + | <!-- |
| - | Photoactive yellow protein (PYP) is a member of the xanthopsin family of eubacterial blue-light photoreceptors. On absorption of light, PYP enters a photocycle that ultimately transduces the energy contained in a light signal into an altered biological response. Nanosecond time-resolved x-ray crystallography was used to determine the structure of the short-lived, red-shifted, intermediate state denoted [pR], which develops within 1 nanosecond after photoelectronic excitation of the chromophore of PYP by absorption of light. The resulting structural model demonstrates that the [pR] state possesses the cis conformation of the 4-hydroxyl cinnamic thioester chromophore, and that the process of trans to cis isomerization is accompanied by the specific formation of new hydrogen bonds that replace those broken upon excitation of the chromophore. Regions of flexibility that compose the chromophore-binding pocket serve to lower the activation energy barrier between the dark state, denoted pG, and [pR], and help initiate entrance into the photocycle. Direct structural evidence is provided for the initial processes of transduction of light energy, which ultimately translate into a physiological signal.
| + | The line below this paragraph, {{ABSTRACT_PUBMED_9506946}}, adds the Publication Abstract to the page |
| | + | (as it appears on PubMed at http://www.pubmed.gov), where 9506946 is the PubMed ID number. |
| | + | --> |
| | + | {{ABSTRACT_PUBMED_9506946}} |
| | | | |
| | ==About this Structure== | | ==About this Structure== |
| Line 36: |
Line 40: |
| | [[Category: Light sensor for negative phototaxis]] | | [[Category: Light sensor for negative phototaxis]] |
| | [[Category: Photoreceptor]] | | [[Category: Photoreceptor]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:01:58 2008'' | + | |
| | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:51:38 2008'' |
Revision as of 08:51, 29 July 2008
Template:STRUCTURE 2pyr
PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)
Template:ABSTRACT PUBMED 9506946
About this Structure
2PYR is a Single protein structure of sequence from Halorhodospira halophila. Full crystallographic information is available from OCA.
Reference
Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle., Perman B, Srajer V, Ren Z, Teng T, Pradervand C, Ursby T, Bourgeois D, Schotte F, Wulff M, Kort R, Hellingwerf K, Moffat K, Science. 1998 Mar 20;279(5358):1946-50. PMID:9506946
Page seeded by OCA on Tue Jul 29 11:51:38 2008
Categories: Halorhodospira halophila | Single protein | Bourgeois, D. | Hellingwerf, K. | Kort, R. | Moffat, K. | Perman, B. | Pradervand, C. | Ren, Z. | Schotte, F. | Srajer, V. | Teng, T Y. | Ursby, T. | Wulff, M. | Light sensor for negative phototaxis | Photoreceptor
