1ql0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ql0.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1ql0.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ql0| PDB=1ql0 | SCENE= }}
{{STRUCTURE_1ql0| PDB=1ql0 | SCENE= }}
-
'''SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT ATOMIC RESOLUTION'''
+
===SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT ATOMIC RESOLUTION===
-
==Overview==
+
<!--
-
The three-dimensional crystal structure of Serratia marcescens endonuclease has been refined at 1.1 A resolution to an R factor of 12.9% and an R(free) of 15.6% with the use of anisotropic temperature factors. The model contains 3694 non-H atoms, 715 water molecules, four sulfate ions and two Mg(2+)-binding sites at the active sites of the homodimeric protein. It is shown that the magnesium ion linked to the active-site Asn119 of each monomer is surrounded by five water molecules and shows an octahedral coordination geometry. The temperature factors for the bound Mg(2+) ions in the A and B subunits are 7.08 and 4.60 A(2), respectively, and the average temperature factors for the surrounding water molecules are 12.13 and 10.3 A(2), respectively. In comparison with earlier structures, alternative side-chain conformations are defined for 51 residues of the dimer, including the essential active-site residue Arg57. A plausible mechanism of enzyme function is proposed based on the high-resolution S. marcescens nuclease structure, the functional characteristics of the natural and mutational forms of the enzyme and consideration of its structural analogy with homing endo-nuclease I-PpoI.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10771425}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10771425 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10771425}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Nuclease]]
[[Category: Nuclease]]
[[Category: Signal]]
[[Category: Signal]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:24:05 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:35:38 2008''

Revision as of 09:35, 29 July 2008

Image:1ql0.png

Template:STRUCTURE 1ql0

SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT ATOMIC RESOLUTION

Template:ABSTRACT PUBMED 10771425

About this Structure

1QL0 is a Single protein structure of sequence from Serratia marcescens. Full crystallographic information is available from OCA.

Reference

Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism., Shlyapnikov SV, Lunin VV, Perbandt M, Polyakov KM, Lunin VY, Levdikov VM, Betzel C, Mikhailov AM, Acta Crystallogr D Biol Crystallogr. 2000 May;56(Pt 5):567-72. PMID:10771425

Page seeded by OCA on Tue Jul 29 12:35:38 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ql0"
Personal tools