2fk6

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[[Image:2fk6.gif|left|200px]]
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{{STRUCTURE_2fk6| PDB=2fk6 | SCENE= }}
{{STRUCTURE_2fk6| PDB=2fk6 | SCENE= }}
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'''Crystal Structure of RNAse Z/tRNA(Thr) complex'''
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===Crystal Structure of RNAse Z/tRNA(Thr) complex===
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==Overview==
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The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.
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{{ABSTRACT_PUBMED_16518398}}
==About this Structure==
==About this Structure==
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[[Category: Trna maturase]]
[[Category: Trna maturase]]
[[Category: Zinc-dependent metal hydrolase]]
[[Category: Zinc-dependent metal hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:59:30 2008''
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Revision as of 10:23, 29 July 2008

Template:STRUCTURE 2fk6

Crystal Structure of RNAse Z/tRNA(Thr) complex

Template:ABSTRACT PUBMED 16518398

About this Structure

2FK6 is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398

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