1ign

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ign.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1ign.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ign| PDB=1ign | SCENE= }}
{{STRUCTURE_1ign| PDB=1ign | SCENE= }}
-
'''DNA-BINDING DOMAIN OF RAP1 IN COMPLEX WITH TELOMERIC DNA SITE'''
+
===DNA-BINDING DOMAIN OF RAP1 IN COMPLEX WITH TELOMERIC DNA SITE===
-
==Overview==
+
<!--
-
Telomeres, the nucleoprotein complexes at the ends of eukaryotic chromosomes, are essential for chromosome stability. In the yeast S. cerevisiae, telomeric DNA is bound in a sequence-specific manner by RAP1, a multifunctional protein also involved in transcriptional regulation. Here we report the crystal structure of the DNA-binding domain of RAP1 in complex with telomeric DNA site at 2.25 A resolution. The protein contains two similar domains that bind DNA in a tandem orientation, recognizing a tandemly repeated DNA sequence. The domains are structurally related to the homeodomain and the proto-oncogene Myb, but show novel features in their DNA-binding mode. A structured linker between the domains and a long C-terminal tail contribute to the binding specificity. This structure provides insight into the recognition of the conserved telomeric DNA sequences by a protein.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8620531}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8620531 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8620531}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Rhodes, D.]]
[[Category: Rhodes, D.]]
[[Category: Rap1,yeast,telomeres,homoeodomain]]
[[Category: Rap1,yeast,telomeres,homoeodomain]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:58:32 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:41:38 2008''

Revision as of 10:41, 29 July 2008

Image:1ign.png

Template:STRUCTURE 1ign

DNA-BINDING DOMAIN OF RAP1 IN COMPLEX WITH TELOMERIC DNA SITE

Template:ABSTRACT PUBMED 8620531

About this Structure

1IGN is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA., Konig P, Giraldo R, Chapman L, Rhodes D, Cell. 1996 Apr 5;85(1):125-36. PMID:8620531

Page seeded by OCA on Tue Jul 29 13:41:38 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ign"
Personal tools