2iub

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[[Image:2iub.gif|left|200px]]
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{{STRUCTURE_2iub| PDB=2iub | SCENE= }}
{{STRUCTURE_2iub| PDB=2iub | SCENE= }}
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'''CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.'''
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===CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.===
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==Overview==
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CorA family members are ubiquitously distributed transporters of divalent metal cations and are considered to be the primary Mg2+ transporter of Bacteria and Archaea. We have determined a 2.9 angstrom resolution structure of CorA from Thermotoga maritima that reveals a pentameric cone-shaped protein. Two potential regulatory metal binding sites are found in the N-terminal domain that bind both Mg2+ and Co2+. The structure of CorA supports an efflux system involving dehydration and rehydration of divalent metal ions potentially mediated by a ring of conserved aspartate residues at the cytoplasmic entrance and a carbonyl funnel at the periplasmic side of the pore.
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(as it appears on PubMed at http://www.pubmed.gov), where 16857941 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16857941}}
==About this Structure==
==About this Structure==
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[[Category: Ion transporter]]
[[Category: Ion transporter]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:53:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:09:08 2008''

Revision as of 11:09, 29 July 2008

Image:2iub.png

Template:STRUCTURE 2iub

CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.

Template:ABSTRACT PUBMED 16857941

About this Structure

2IUB is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution., Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P, Science. 2006 Jul 21;313(5785):354-7. PMID:16857941

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