2ivf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2ivf.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2ivf.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ivf| PDB=2ivf | SCENE= }}
{{STRUCTURE_2ivf| PDB=2ivf | SCENE= }}
-
'''ETHYLBENZENE DEHYDROGENASE FROM AROMATOLEUM AROMATICUM'''
+
===ETHYLBENZENE DEHYDROGENASE FROM AROMATOLEUM AROMATICUM===
-
==Overview==
+
<!--
-
Anaerobic degradation of hydrocarbons was discovered a decade ago, and ethylbenzene dehydrogenase was one of the first characterized enzymes involved. The structure of the soluble periplasmic 165 kDa enzyme was established at 1.88 A resolution. It is a heterotrimer. The alpha subunit contains the catalytic center with a molybdenum held by two molybdopterin-guanine dinucleotides, one with an open pyran ring, and an iron-sulfur cluster with a histidine ligand. During catalysis, electrons produced by substrate oxidation are transferred to a heme in the gamma subunit and then presumably to a separate cytochrome involved in nitrate respiration. The beta subunit contains four iron-sulfur clusters and is structurally related to ferredoxins. The gamma subunit is the first known protein with a methionine and a lysine as axial heme ligands. The catalytic product was modeled into the active center, showing the reaction geometry. A mechanism consistent with activity and inhibition data of ethylbenzene-related compounds is proposed.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16962969}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16962969 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16962969}}
==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Moco]]
[[Category: Moco]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:56:07 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:09:18 2008''

Revision as of 11:09, 29 July 2008

Image:2ivf.png

Template:STRUCTURE 2ivf

ETHYLBENZENE DEHYDROGENASE FROM AROMATOLEUM AROMATICUM

Template:ABSTRACT PUBMED 16962969

About this Structure

2IVF is a Protein complex structure of sequences from Azoarcus sp. eb1. Full crystallographic information is available from OCA.

Reference

Crystal structure of ethylbenzene dehydrogenase from Aromatoleum aromaticum., Kloer DP, Hagel C, Heider J, Schulz GE, Structure. 2006 Sep;14(9):1377-88. PMID:16962969

Page seeded by OCA on Tue Jul 29 14:09:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ivf"
Personal tools