We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1t98

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1t98.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1t98.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1t98| PDB=1t98 | SCENE= }}
{{STRUCTURE_1t98| PDB=1t98 | SCENE= }}
-
'''Crystal Structure of MukF(1-287)'''
+
===Crystal Structure of MukF(1-287)===
-
==Overview==
+
<!--
-
The Escherichia coli MukB, MukE, and MukF proteins form a bacterial condensin (MukBEF) that contributes to chromosome management by compacting DNA. MukB is an ATPase and DNA-binding protein of the SMC superfamily; however, the structure and function of non-SMC components, such as MukF, have been less forthcoming. Here, we report the crystal structure of the N-terminal 287 amino acids of MukF at 2.9 A resolution. This region folds into a winged-helix domain and an extended coiled-coil domain that self-associate to form a stable, doubly domain-swapped dimer. Protein dissection and affinity purification data demonstrate that the region of MukF C-terminal to this fragment binds to MukE and MukB. Our findings, together with sequence analyses, indicate that MukF is a kleisin subunit for E. coli condensin and suggest a means by which it may organize the MukBEF assembly.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15902272}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15902272 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15902272}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Helix-turn helix]]
[[Category: Helix-turn helix]]
[[Category: Winged helix]]
[[Category: Winged helix]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:41:46 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:19:35 2008''

Revision as of 11:19, 29 July 2008

Image:1t98.png

Template:STRUCTURE 1t98

Crystal Structure of MukF(1-287)

Template:ABSTRACT PUBMED 15902272

About this Structure

1T98 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins., Fennell-Fezzie R, Gradia SD, Akey D, Berger JM, EMBO J. 2005 Jun 1;24(11):1921-30. Epub 2005 May 19. PMID:15902272

Page seeded by OCA on Tue Jul 29 14:19:35 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1t98"
Personal tools