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1sla

From Proteopedia

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[[Image:1sla.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1sla| PDB=1sla | SCENE= }}
{{STRUCTURE_1sla| PDB=1sla | SCENE= }}
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'''X-RAY CRYSTALLOGRAPHY REVEALS CROSSLINKING OF MAMMALIAN LECTIN (GALECTIN-1) BY BIANTENNARY COMPLEX TYPE SACCHARIDES'''
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===X-RAY CRYSTALLOGRAPHY REVEALS CROSSLINKING OF MAMMALIAN LECTIN (GALECTIN-1) BY BIANTENNARY COMPLEX TYPE SACCHARIDES===
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==Overview==
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Galectins are beta-galactoside-binding proteins that occur intra- and extracellularly in many animal tissues. They have been proposed to form networks of glycoconjugates on the cell surface, where they may modulate various cell response pathways such as growth, activation and adhesion. The high resolution X-ray crystallographic analyses of three crystal forms of bovine galectin-1 in complex with biantennary saccharides of N-acetyllactosamine type reveal infinite chains of lectin dimers cross-linked through N-acetyllactosamine units located at the end of the oligosaccharide antenna. The oligosaccharide adopts a different low energy conformation in each of the three crystal forms.
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The line below this paragraph, {{ABSTRACT_PUBMED_7773775}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7773775 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7773775}}
==About this Structure==
==About this Structure==
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[[Category: Bourne, Y.]]
[[Category: Bourne, Y.]]
[[Category: Cambillau, C.]]
[[Category: Cambillau, C.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:50:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:29:45 2008''

Revision as of 11:29, 29 July 2008

Image:1sla.png

Template:STRUCTURE 1sla

X-RAY CRYSTALLOGRAPHY REVEALS CROSSLINKING OF MAMMALIAN LECTIN (GALECTIN-1) BY BIANTENNARY COMPLEX TYPE SACCHARIDES

Template:ABSTRACT PUBMED 7773775

About this Structure

1SLA is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides., Bourne Y, Bolgiano B, Liao DI, Strecker G, Cantau P, Herzberg O, Feizi T, Cambillau C, Nat Struct Biol. 1994 Dec;1(12):863-70. PMID:7773775

Page seeded by OCA on Tue Jul 29 14:29:45 2008

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