2ixq

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[[Image:2ixq.gif|left|200px]]
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[[Image:2ixq.png|left|200px]]
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{{STRUCTURE_2ixq| PDB=2ixq | SCENE= }}
{{STRUCTURE_2ixq| PDB=2ixq | SCENE= }}
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'''THE SOLUTION STRUCTURE OF THE INVASIVE TIP COMPLEX FROM AFA-DR FIBRILS'''
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===THE SOLUTION STRUCTURE OF THE INVASIVE TIP COMPLEX FROM AFA-DR FIBRILS===
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==Overview==
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Afa/Dr family of adhesins are produced by pathogenic Escherichia coli strains that are especially prevalent in chronic diarrhoeal and recurrent urinary tract infections. Most notably, they are found in up to 50% of cystitis cases in children and 30% of pyelonephritis in pregnant women. Afa/Dr adhesins are capped surface fibrils that mediate recognition of the host and subsequent bacterial internalization. Using the newly solved three-dimensional structure of the minimal invasive complex (AfaDE) combined with biochemical and cellular assays, we reveal the architecture of the fibrillar cap and identify a novel mode of synergistic integrin recognition.
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The line below this paragraph, {{ABSTRACT_PUBMED_16965519}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16965519 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16965519}}
==About this Structure==
==About this Structure==
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2IXQ is a [[Protein complex]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXQ OCA].
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2IXQ is a [[Protein complex]] structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXQ OCA].
==Reference==
==Reference==
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[[Category: Structural protein]]
[[Category: Structural protein]]
[[Category: Upec]]
[[Category: Upec]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:02:50 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:36:45 2008''

Revision as of 11:36, 29 July 2008

Image:2ixq.png

Template:STRUCTURE 2ixq

THE SOLUTION STRUCTURE OF THE INVASIVE TIP COMPLEX FROM AFA-DR FIBRILS

Template:ABSTRACT PUBMED 16965519

About this Structure

2IXQ is a Protein complex structure. Full experimental information is available from OCA.

Reference

The solution structure of the invasive tip complex from Afa/Dr fibrils., Cota E, Jones C, Simpson P, Altroff H, Anderson KL, du Merle L, Guignot J, Servin A, Le Bouguenec C, Mardon H, Matthews S, Mol Microbiol. 2006 Oct;62(2):356-66. Epub 2006 Sep 8. PMID:16965519

Page seeded by OCA on Tue Jul 29 14:36:45 2008

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