1t00

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[[Image:1t00.gif|left|200px]]
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{{STRUCTURE_1t00| PDB=1t00 | SCENE= }}
{{STRUCTURE_1t00| PDB=1t00 | SCENE= }}
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'''The structure of thioredoxin from S. coelicolor'''
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===The structure of thioredoxin from S. coelicolor===
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==Overview==
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Thioredoxins are ubiquitous proteins that serve as reducing agents and general protein disulfide reductases. In turn, they are reduced by electrons obtained from the NADPH-containing thioredoxin reductase. Thioredoxins have been isolated and characterized from a large number of organisms. The Gram-positive bacterium Streptomyces coelicolor contains three thioredoxins that are involved in unknown biological processes. trxA from S. coelicolor was cloned and expressed in Escherichia coli and the protein purified and crystallized using the hanging-drop method of vapour diffusion. The crystal structure of thioredoxin A has been determined at 1.5 A resolution using a synchrotron-radiation source. The protein reveals a thioredoxin-like fold with a typical CXXC active site. The crystal exhibits the symmetry of space group P2(1)2(1)2, with unit-cell parameters a = 43.6, b = 71.8, c = 33.2 A.
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The line below this paragraph, {{ABSTRACT_PUBMED_16510983}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16510983 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16510983}}
==About this Structure==
==About this Structure==
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[[Category: Structure]]
[[Category: Structure]]
[[Category: Thioredoxin]]
[[Category: Thioredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:20:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:44:36 2008''

Revision as of 11:44, 29 July 2008

Image:1t00.png

Template:STRUCTURE 1t00

The structure of thioredoxin from S. coelicolor

Template:ABSTRACT PUBMED 16510983

About this Structure

1T00 is a Single protein structure of sequence from Streptomyces coelicolor. Full crystallographic information is available from OCA.

Reference

Expression, purification and X-ray crystallographic analysis of thioredoxin from Streptomyces coelicolor., Stefankova P, Maderova J, Barak I, Kollarova M, Otwinowski Z, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt, 2):164-8. Epub 2005 Jan 8. PMID:16510983

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