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1jy5

From Proteopedia

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{{STRUCTURE_1jy5| PDB=1jy5 | SCENE= }}
{{STRUCTURE_1jy5| PDB=1jy5 | SCENE= }}
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'''RNase-related protein from Calystegia sepium'''
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===RNase-related protein from Calystegia sepium===
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==Overview==
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The structure of a catalytically inactive RNase-related protein from Calystegia sepium (CalsepRRP) has been resolved by protein crystallography at a resolution of 2.05 A and an R factor of 20.74%. Although the protein is completely devoid of ribonuclease activity, it adopts the typical alpha + beta structure of non-base-specific RNases. Analysis of the structure revealed that two amino-acid substitutions in the 'active' P1 site, in combination with the less hydrophobic/aromatic character of the B1 base-recognition site and a completely disrupted B2 base-recognition site, might account for this complete lack of activity.
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(as it appears on PubMed at http://www.pubmed.gov), where 11914487 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11914487}}
==About this Structure==
==About this Structure==
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[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Rnase]]
[[Category: Rnase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:03:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:11:53 2008''

Revision as of 12:11, 29 July 2008

Image:1jy5.png

Template:STRUCTURE 1jy5

RNase-related protein from Calystegia sepium

Template:ABSTRACT PUBMED 11914487

About this Structure

1JY5 is a Single protein structure of sequence from Calystegia sepium. Full crystallographic information is available from OCA.

Reference

Structure of an RNase-related protein from Calystegia sepium., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:11914487

Page seeded by OCA on Tue Jul 29 15:11:53 2008

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