1oyt
From Proteopedia
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{{STRUCTURE_1oyt| PDB=1oyt | SCENE= }} | {{STRUCTURE_1oyt| PDB=1oyt | SCENE= }} | ||
| - | + | ===COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR=== | |
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[[Category: Banner, D W.]] | [[Category: Banner, D W.]] | ||
[[Category: Olsen, J A.]] | [[Category: Olsen, J A.]] | ||
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Revision as of 12:28, 29 July 2008
Contents |
COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1OYT is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions., Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Muller K, Diederich F, Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2507-11. PMID:12800172
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