1rpr

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{{STRUCTURE_1rpr| PDB=1rpr | SCENE= }}
{{STRUCTURE_1rpr| PDB=1rpr | SCENE= }}
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'''THE STRUCTURE OF COLE1 ROP IN SOLUTION'''
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===THE STRUCTURE OF COLE1 ROP IN SOLUTION===
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==Overview==
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The structure of the ColE1 repressor of primer (rop) protein in solution was determined from the proton nuclear magnetic resonance data by a combined use of distance geometry and restrained molecular dynamics calculations. A set of structures was determined with low internal energy and virtually no violations of the experimental distance restraints. Rop forms homodimers: Two helical hairpins are arranged as an antiparallel four helix bundle with a left-handed rope-like twist of the helix axes and with left-handed bundle topology. The very compact packing of the side chains in the helix interfaces of the rop coiled-coil structure may well account for its high stability. Overall, the solution structure is highly similar to the recently determined X-ray structure (Banner, D.W., Kokkinidis, M. and Tsernoglou, D. (1987) J. Mol. Biol., 196, 657-675), although there are minor differences in regions where packing forces appear to influence the crystal structure.
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(as it appears on PubMed at http://www.pubmed.gov), where 1841691 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1841691}}
==About this Structure==
==About this Structure==
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1RPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPR OCA].
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1RPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPR OCA].
==Reference==
==Reference==
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[[Category: Sander, C.]]
[[Category: Sander, C.]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:00:43 2008''

Revision as of 13:00, 29 July 2008

Image:1rpr.png

Template:STRUCTURE 1rpr

THE STRUCTURE OF COLE1 ROP IN SOLUTION

Template:ABSTRACT PUBMED 1841691

About this Structure

1RPR is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

The structure of ColE1 rop in solution., Eberle W, Pastore A, Sander C, Rosch P, J Biomol NMR. 1991 May;1(1):71-82. PMID:1841691

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