3cen

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_3cen", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
Line 1: Line 1:
-
[[Image:3cen.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:3cen.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_3cen| PDB=3cen | SCENE= }}
{{STRUCTURE_3cen| PDB=3cen | SCENE= }}
-
'''Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide'''
+
===Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide===
-
==Overview==
+
<!--
-
Introduction of the phenyl piperidinone and phenyl pyridinone P4 moieties in the anthranilamide scaffold led to potent, selective, and orally bioavailable inhibitors of factor Xa. Anthranilamide 28 displayed comparable efficacy to apixaban in the rabbit arteriovenous-shunt (AV) thrombosis model.
+
The line below this paragraph, {{ABSTRACT_PUBMED_18424044}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 18424044 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_18424044}}
==About this Structure==
==About this Structure==
Line 37: Line 41:
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:01:04 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:17:15 2008''

Revision as of 13:17, 29 July 2008

Image:3cen.png

Template:STRUCTURE 3cen

Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide

Template:ABSTRACT PUBMED 18424044

About this Structure

3CEN is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties., Corte JR, Fang T, Pinto DJ, Han W, Hu Z, Jiang XJ, Li YL, Gauuan JF, Hadden M, Orton D, Rendina AR, Luettgen JM, Wong PC, He K, Morin PE, Chang CH, Cheney DL, Knabb RM, Wexler RR, Lam PY, Bioorg Med Chem Lett. 2008 May 1;18(9):2845-9. Epub 2008 Apr 8. PMID:18424044

Page seeded by OCA on Tue Jul 29 16:17:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3cen"
Personal tools