1o84

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1o84.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1o84.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1o84| PDB=1o84 | SCENE= }}
{{STRUCTURE_1o84| PDB=1o84 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.'''
+
===CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.===
-
==Overview==
+
<!--
-
The bacteriocin AS-48 is a membrane-interacting peptide, which displays a broad anti-microbial spectrum against Gram-positive and Gram-negative bacteria. The NMR structure of AS-48 at pH 3 has been solved. The analysis of this structure suggests that the mechanism of AS-48 anti-bacterial activity involves the accumulation of positively charged molecules at the membrane surface leading to a disruption of the membrane potential. Here, we report the high-resolution crystal structure of AS-48 and sedimentation equilibrium experiments showing that this bacteriocin is able to adopt different oligomeric structures according to the physicochemical environment. The analysis of these structures suggests a mechanism for molecular function of AS-48 involving a transition from a water-soluble form to a membrane-bound state upon membrane binding.
+
The line below this paragraph, {{ABSTRACT_PUBMED_14623193}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14623193 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14623193}}
==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Protein crystallography]]
[[Category: Protein crystallography]]
[[Category: Protein membrane interaction]]
[[Category: Protein membrane interaction]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:30:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:37:25 2008''

Revision as of 13:37, 29 July 2008

Image:1o84.png

Template:STRUCTURE 1o84

CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.

Template:ABSTRACT PUBMED 14623193

About this Structure

1O84 is a Single protein structure of sequence from Enterococcus faecalis. Full crystallographic information is available from OCA.

Reference

Structure of bacteriocin AS-48: from soluble state to membrane bound state., Sanchez-Barrena MJ, Martinez-Ripoll M, Galvez A, Valdivia E, Maqueda M, Cruz V, Albert A, J Mol Biol. 2003 Nov 28;334(3):541-9. PMID:14623193

Page seeded by OCA on Tue Jul 29 16:37:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o84"
Personal tools