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2rgp

From Proteopedia

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(New page: '''Unreleased structure''' The entry 2rgp is ON HOLD until Paper Publication Authors: Abad, M.C. Description: Structure of EGFR in complex with hydrazone, a potent dual inhibitor ''P...)
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'''Unreleased structure'''
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[[Image:2rgp.jpg|left|200px]]
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The entry 2rgp is ON HOLD until Paper Publication
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{{STRUCTURE_2rgp| PDB=2rgp | SCENE= }}
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Authors: Abad, M.C.
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===Structure of EGFR in complex with hydrazone, a potent dual inhibitor===
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Description: Structure of EGFR in complex with hydrazone, a potent dual inhibitor
 
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{{ABSTRACT_PUBMED_18653333}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 08:48:53 2008''
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==About this Structure==
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2RGP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGP OCA].
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==Reference==
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4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors., Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18653333 18653333]
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
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[[Category: Abad, M C.]]
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[[Category: Alternative splicing]]
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[[Category: Anti-oncogene]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Disease mutation]]
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[[Category: Glycoprotein]]
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[[Category: Kinase domain]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Receptor]]
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[[Category: Secreted]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Tyrosine-protein kinase]]
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[[Category: Ubl conjugation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:09:10 2008''

Revision as of 08:09, 27 August 2008

Image:2rgp.jpg

Template:STRUCTURE 2rgp

Structure of EGFR in complex with hydrazone, a potent dual inhibitor

Template:ABSTRACT PUBMED 18653333

About this Structure

2RGP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors., Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333

Page seeded by OCA on Wed Aug 27 11:09:10 2008

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