3d14
From Proteopedia
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| + | [[Image:3d14.jpg|left|200px]] | ||
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| + | {{STRUCTURE_3d14| PDB=3d14 | SCENE= }} | ||
| - | + | ===Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea=== | |
| - | Description: Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]-thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_18678489}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 18678489 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_18678489}} | ||
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| + | ==About this Structure== | ||
| + | 3D14 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D14 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | Discovery of a potent and selective Aurora kinase inhibitor., Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W, Bioorg Med Chem Lett. 2008 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18678489 18678489] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Single protein]] | ||
| + | [[Category: Allen, D A.]] | ||
| + | [[Category: Baskaran, S.]] | ||
| + | [[Category: Elling, R A.]] | ||
| + | [[Category: Oslob, J D.]] | ||
| + | [[Category: Romanowski, M J.]] | ||
| + | [[Category: Aurora some]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Small-molecule inhibitor]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:27:17 2008'' | ||
Revision as of 08:27, 27 August 2008
Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea
Template:ABSTRACT PUBMED 18678489
About this Structure
3D14 is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
Discovery of a potent and selective Aurora kinase inhibitor., Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W, Bioorg Med Chem Lett. 2008 Jul 24. PMID:18678489
Page seeded by OCA on Wed Aug 27 11:27:17 2008
