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3dox
From Proteopedia
(New page: '''Unreleased structure''' The entry 3dox is ON HOLD until Paper Publication Authors: Bihani, S.C., Das, A., Prashar, V., Ferrer, J.L., Hosur, M.V. Description: X-ray structure of HIV-...) |
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| + | [[Image:3dox.jpg|left|200px]] | ||
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| + | {{STRUCTURE_3dox| PDB=3dox | SCENE= }} | ||
| - | + | ===X-ray structure of HIV-1 protease in situ product complex=== | |
| - | Description: X-ray structure of HIV-1 protease in situ product complex | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_18704947}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 18704947 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_18704947}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3DOX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2_group_m_subtype_b) Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOX OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | X-ray structure of HIV-1 protease in situ product complex., Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV, Proteins. 2008 Aug 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18704947 18704947] | ||
| + | |||
| + | 1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR., Pillai B, Kannan KK, Hosur MV, Proteins. 2001 Apr 1;43(1):57-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11170214 11170214] | ||
| + | |||
| + | Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex., Kumar M, Prashar V, Mahale S, Hosur MV, Biochem J. 2005 Jul 15;389(Pt 2):365-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15794743 15794743] | ||
| + | |||
| + | Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction., Pillai B, Kannan KK, Bhat SV, Hosur MV, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):594-6. Epub 2004, Feb 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14993705 14993705] | ||
| + | |||
| + | Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates., Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV, Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. Epub 2006 Nov 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17116869 17116869] | ||
| + | [[Category: HIV-1 retropepsin]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Bihani, S.]] | ||
| + | [[Category: Das, A.]] | ||
| + | [[Category: Ferrer, J L.]] | ||
| + | [[Category: Hosur, M V.]] | ||
| + | [[Category: Prashar, V.]] | ||
| + | [[Category: Aid]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Capsid maturation]] | ||
| + | [[Category: Capsid protein]] | ||
| + | [[Category: Catalysis]] | ||
| + | [[Category: Cytoplasm]] | ||
| + | [[Category: Dna integration]] | ||
| + | [[Category: Dna recombination]] | ||
| + | [[Category: Dna-directed dna polymerase]] | ||
| + | [[Category: Endonuclease]] | ||
| + | [[Category: Hiv-1 protease]] | ||
| + | [[Category: Host-virus interaction]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lipoprotein]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Multifunctional enzyme]] | ||
| + | [[Category: Myristate]] | ||
| + | [[Category: Nuclease]] | ||
| + | [[Category: Nucleotidyltransferase]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Reaction intermediate]] | ||
| + | [[Category: Ribosomal frameshifting]] | ||
| + | [[Category: Rna-binding]] | ||
| + | [[Category: Rna-directed dna polymerase]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transition state]] | ||
| + | [[Category: Viral nucleoprotein]] | ||
| + | [[Category: Virion]] | ||
| + | [[Category: X-ray crystallography]] | ||
| + | [[Category: Zinc]] | ||
| + | [[Category: Zinc-finger]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 10:33:05 2008'' | ||
Revision as of 07:33, 10 September 2008
X-ray structure of HIV-1 protease in situ product complex
Template:ABSTRACT PUBMED 18704947
About this Structure
3DOX is a Protein complex structure of sequences from Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b). Full crystallographic information is available from OCA.
Reference
X-ray structure of HIV-1 protease in situ product complex., Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV, Proteins. 2008 Aug 14. PMID:18704947
1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR., Pillai B, Kannan KK, Hosur MV, Proteins. 2001 Apr 1;43(1):57-64. PMID:11170214
Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex., Kumar M, Prashar V, Mahale S, Hosur MV, Biochem J. 2005 Jul 15;389(Pt 2):365-71. PMID:15794743
Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction., Pillai B, Kannan KK, Bhat SV, Hosur MV, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):594-6. Epub 2004, Feb 25. PMID:14993705
Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates., Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV, Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. Epub 2006 Nov 20. PMID:17116869
Page seeded by OCA on Wed Sep 10 10:33:05 2008
Categories: HIV-1 retropepsin | Protein complex | Bihani, S. | Das, A. | Ferrer, J L. | Hosur, M V. | Prashar, V. | Aid | Aspartyl protease | Capsid maturation | Capsid protein | Catalysis | Cytoplasm | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv-1 protease | Host-virus interaction | Hydrolase | Inhibitor | Lipoprotein | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nuclease | Nucleotidyltransferase | Nucleus | Phosphoprotein | Protease | Reaction intermediate | Ribosomal frameshifting | Rna-binding | Rna-directed dna polymerase | Transferase | Transition state | Viral nucleoprotein | Virion | X-ray crystallography | Zinc | Zinc-finger
