2r7b

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(New page: '''Unreleased structure''' The entry 2r7b is ON HOLD until Sep 07 2009 Authors: Olland, A.M. Description: Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic ...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2r7b.jpg|left|200px]]
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The entry 2r7b is ON HOLD until Sep 07 2009
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{{STRUCTURE_2r7b| PDB=2r7b | SCENE= }}
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Authors: Olland, A.M.
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===Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor===
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Description: Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor
 
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{{ABSTRACT_PUBMED_17941624}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 08:47:46 2008''
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==About this Structure==
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2R7B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7B OCA].
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==Reference==
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Discovery of dibenzo[c,f][2,7]naphthyridines as potent and selective 3-phosphoinositide-dependent kinase-1 inhibitors., Gopalsamy A, Shi M, Boschelli DH, Williamson R, Olland A, Hu Y, Krishnamurthy G, Han X, Arndt K, Guo B, J Med Chem. 2007 Nov 15;50(23):5547-9. Epub 2007 Oct 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17941624 17941624]
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
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[[Category: Olland, A M.]]
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[[Category: Dibenzonaphthyridine]]
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[[Category: Inhibitor]]
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[[Category: Pdk1]]
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[[Category: Signaling protein]]
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[[Category: Structure]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 10:41:37 2008''

Revision as of 07:41, 10 September 2008

Image:2r7b.jpg

Template:STRUCTURE 2r7b

Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor

Template:ABSTRACT PUBMED 17941624

About this Structure

2R7B is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of dibenzo[c,f][2,7]naphthyridines as potent and selective 3-phosphoinositide-dependent kinase-1 inhibitors., Gopalsamy A, Shi M, Boschelli DH, Williamson R, Olland A, Hu Y, Krishnamurthy G, Han X, Arndt K, Guo B, J Med Chem. 2007 Nov 15;50(23):5547-9. Epub 2007 Oct 17. PMID:17941624

Page seeded by OCA on Wed Sep 10 10:41:37 2008

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