This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1sfo
From Proteopedia
OCA (Talk | contribs)
(New page: 200px<br /><applet load="1sfo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sfo, resolution 3.61Å" /> '''RNA POLYMERASE II ST...)
Next diff →
Revision as of 00:13, 21 November 2007
|
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
Overview
The structure of an RNA polymerase II-transcribing complex has been, determined in the posttranslocation state, with a vacancy at the growing, end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid, strands is brought about by interaction with a set of proteins loops in a, strand/loop network. Formation of the network must occur in the transition, from abortive initiation to promoter escape.
About this Structure
1SFO is a Protein complex structure of sequences from Saccharomyces cerevisiae with ZN and MG as ligands. This structure superseeds the now removed PDB entry 1R9R. Active as DNA-directed RNA polymerase, with EC number 2.7.7.6 Full crystallographic information is available from OCA.
Reference
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II., Westover KD, Bushnell DA, Kornberg RD, Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331
Page seeded by OCA on Wed Nov 21 02:21:11 2007
