1sro
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(New page: 200px<br /><applet load="1sro" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sro" /> '''S1 RNA BINDING DOMAIN, NMR, 20 STRUCTURES'''...)
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Revision as of 00:29, 21 November 2007
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S1 RNA BINDING DOMAIN, NMR, 20 STRUCTURES
Overview
The S1 domain, originally identified in ribosomal protein S1, is found in, a large number of RNA-associated proteins. The structure of the S1, RNA-binding domain from the E. coli polynucleotide phosphorylase has been, determined using NMR methods and consists of a five-stranded antiparallel, beta barrel. Conserved residues on one face of the barrel and adjacent, loops form the putative RNA-binding site. The structure of the S1 domain, is very similar to that of cold shock protein, suggesting that they are, both derived from an ancient nucleic acid-binding protein. Enhanced, sequence searches reveal hitherto unidentified S1 domains in RNase E, RNase II, NusA, EMB-5, and other proteins.
About this Structure
1SRO is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
The solution structure of the S1 RNA binding domain: a member of an ancient nucleic acid-binding fold., Bycroft M, Hubbard TJ, Proctor M, Freund SM, Murzin AG, Cell. 1997 Jan 24;88(2):235-42. PMID:9008164
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