3efk

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3efk.jpg|left|200px]]
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The entry 3efk is ON HOLD
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{{STRUCTURE_3efk| PDB=3efk | SCENE= }}
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Authors: Bellon, S.F., D'Angelo, N., Whittington, D., Dussault, I.
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===Structure of c-Met with pyrimidone inhibitor 50===
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Description: Structure of c-Met with pyrimidone inhibitor 50
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 24 10:15:05 2008''
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{{ABSTRACT_PUBMED_18763753}}
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==Disease==
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Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
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==About this Structure==
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3EFK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFK OCA].
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==Reference==
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Design, synthesis, and biological evaluation of potent c-Met inhibitors., D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS, J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18763753 18763753]
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
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[[Category: Angelo, N D.]]
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[[Category: Bellon, S F.]]
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[[Category: Dussault, I.]]
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[[Category: Whittington, D.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: C-met]]
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[[Category: Chromosomal rearrangement]]
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[[Category: Disease mutation]]
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[[Category: Glycoprotein]]
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[[Category: Kinase]]
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[[Category: Kinase inhibitor pyrimidone]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Proto-oncogene]]
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[[Category: Receptor]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:36:24 2008''

Revision as of 07:36, 8 October 2008

Image:3efk.jpg

Template:STRUCTURE 3efk

Contents

Structure of c-Met with pyrimidone inhibitor 50

Template:ABSTRACT PUBMED 18763753

Disease

Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]

About this Structure

3EFK is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design, synthesis, and biological evaluation of potent c-Met inhibitors., D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS, J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753

Page seeded by OCA on Wed Oct 8 09:36:24 2008

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