3bdj

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3bdj.jpg|left|200px]]
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The entry 3bdj is ON HOLD until Nov 21 2009
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{{STRUCTURE_3bdj| PDB=3bdj | SCENE= }}
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Authors: Eger, B.T., Okamoto, K., Nishino, T., Pai, E.F., Nishino, T.
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===Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor===
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Description: Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:36:41 2008''
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{{ABSTRACT_PUBMED_18600558}}
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==About this Structure==
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3BDJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BDJ OCA].
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==Reference==
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Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol., Okamoto K, Eger BT, Nishino T, Pai EF, Nishino T, Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):888-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18600558 18600558]
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Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus., Truglio JJ, Theis K, Leimkuhler S, Rappa R, Rajagopalan KV, Kisker C, Structure. 2002 Jan;10(1):115-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11796116 11796116]
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The crystal structure of xanthine oxidoreductase during catalysis: implications for reaction mechanism and enzyme inhibition., Okamoto K, Matsumoto K, Hille R, Eger BT, Pai EF, Nishino T, Proc Natl Acad Sci U S A. 2004 May 25;101(21):7931-6. Epub 2004 May 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15148401 15148401]
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Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion., Fukunari A, Okamoto K, Nishino T, Eger BT, Pai EF, Kamezawa M, Yamada I, Kato N, J Pharmacol Exp Ther. 2004 Nov;311(2):519-28. Epub 2004 Jun 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15190124 15190124]
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An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition., Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T, J Biol Chem. 2003 Jan 17;278(3):1848-55. Epub 2002 Nov 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12421831 12421831]
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[[Category: Bos taurus]]
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[[Category: Eger, B T.]]
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[[Category: Nishino, T.]]
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[[Category: Okamoto, K.]]
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[[Category: Pai, E F.]]
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[[Category: 2fe-2]]
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[[Category: Allopurinol]]
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[[Category: Alloxanthine]]
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[[Category: Covalently bound inhibitor]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Iron-sulfur]]
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[[Category: Molybdopterin]]
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[[Category: Oxipurinol]]
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[[Category: Oxypurinol]]
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[[Category: Peroxisome]]
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[[Category: Xanthine dehydrogenase]]
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[[Category: Xanthine oxidase]]
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[[Category: Xanthine oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 27 13:33:40 2008''

Revision as of 11:33, 27 November 2008

Image:3bdj.jpg

Template:STRUCTURE 3bdj

Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor

Template:ABSTRACT PUBMED 18600558

About this Structure

3BDJ is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol., Okamoto K, Eger BT, Nishino T, Pai EF, Nishino T, Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):888-93. PMID:18600558

Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus., Truglio JJ, Theis K, Leimkuhler S, Rappa R, Rajagopalan KV, Kisker C, Structure. 2002 Jan;10(1):115-25. PMID:11796116

The crystal structure of xanthine oxidoreductase during catalysis: implications for reaction mechanism and enzyme inhibition., Okamoto K, Matsumoto K, Hille R, Eger BT, Pai EF, Nishino T, Proc Natl Acad Sci U S A. 2004 May 25;101(21):7931-6. Epub 2004 May 17. PMID:15148401

Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion., Fukunari A, Okamoto K, Nishino T, Eger BT, Pai EF, Kamezawa M, Yamada I, Kato N, J Pharmacol Exp Ther. 2004 Nov;311(2):519-28. Epub 2004 Jun 9. PMID:15190124

An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition., Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T, J Biol Chem. 2003 Jan 17;278(3):1848-55. Epub 2002 Nov 5. PMID:12421831

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