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3f6u

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Revision as of 07:51, 5 December 2008

Image:3f6u.png

Template:STRUCTURE 3f6u

Crystal structure of human Activated Protein C (APC) complexed with PPACK

Template:ABSTRACT PUBMED 12029084

About this Structure

3F6U is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops., Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP, J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:12029084

The 2.8 A crystal structure of Gla-domainless activated protein C., Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W, EMBO J. 1996 Dec 16;15(24):6822-31. PMID:9003757

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