Sandbox2qc8
From Proteopedia
(Difference between revisions)
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Glutamine synthetase is composed of 10 <scene name='Sandbox2qc8/Secondary_structure/1'>identical subunits</scene>. | Glutamine synthetase is composed of 10 <scene name='Sandbox2qc8/Secondary_structure/1'>identical subunits</scene>. | ||
| - | Each subunit has an exposed NH2 terminus and buried COOH terminus. <ref>Yamashita, M., et al.,Refined Atomic Model of Glutamine Synthetase at 3.5A Resolution, The Journal of Biological Chemistry, 1989, 17681-17690.</ref> | + | Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. <ref>Yamashita, M., et al.,Refined Atomic Model of Glutamine Synthetase at 3.5A Resolution, The Journal of Biological Chemistry, 1989, 17681-17690.</ref> |
Each subunit is composed predominantly of 12 <scene name='Sandbox2qc8/Subunit_alpha/1'>alpha helices</scene> and 12 | Each subunit is composed predominantly of 12 <scene name='Sandbox2qc8/Subunit_alpha/1'>alpha helices</scene> and 12 | ||
Revision as of 03:00, 8 December 2008
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| 2qc8, resolution 2.60Å () | |||||||||
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| Ligands: | , , , | ||||||||
| Gene: | GLUL, GLNS (Homo sapiens) | ||||||||
| Activity: | Glutamate--ammonia ligase, with EC number 6.3.1.2 | ||||||||
| Related: | 2ojw | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
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Glutamine synthetase is composed of 10 .
Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. [1]
Each subunit is composed predominantly of 12 and 12 , as well as a .
The beta sheets are arranged into two separate partial beta barrels, one of which encompasses the ligand complex.
The active site within the secondary structure can be called a "bifunnel," providing access to ATP and glutamate at opposing ends.[2]
The ligands present are Cl, Mn, Adenosine Diphosphate, and L-Methionine-S-Sulfoximine Phosphate.
