2ze1

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(New page: '''Unreleased structure''' The entry 2ze1 is ON HOLD until Dec 05 2009 Authors: Cole, D.C., Stock, J.R., Chopra, R., Cowling, R., Ellingboe, J.W., Fan, K.Y., Harrison, B.L., Hu, Y., Jac...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2ze1.jpg|left|200px]]
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The entry 2ze1 is ON HOLD until Dec 05 2009
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{{STRUCTURE_2ze1| PDB=2ze1 | SCENE= }}
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Authors: Cole, D.C., Stock, J.R., Chopra, R., Cowling, R., Ellingboe, J.W., Fan, K.Y., Harrison, B.L., Hu, Y., Jacobsen, S., Jennings, L.D., Jin, G., Lohse, P.A., Malamas, M.S., Manas, E.S., Moore, W.J., O'Donnell, M., Robichaud, A.J., Svenson, K., Wu, J., Wagner,
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===X-ray structure of Bace-1 in complex with compound 6g===
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Description: X-ray structure of Bace-1 in complex with compound 6g
 
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{{ABSTRACT_PUBMED_18162398}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:07:48 2008''
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==About this Structure==
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2ZE1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZE1 OCA].
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==Reference==
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Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets., Cole DC, Stock JR, Chopra R, Cowling R, Ellingboe JW, Fan KY, Harrison BL, Hu Y, Jacobsen S, Jennings LD, Jin G, Lohse PA, Malamas MS, Manas ES, Moore WJ, O'Donnell MM, Olland AM, Robichaud AJ, Svenson K, Wu J, Wagner E, Bard J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1063-6. Epub 2007 Dec 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18162398 18162398]
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Chopra, R.]]
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[[Category: Olland, A.]]
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[[Category: Acylguanidine inhibitor]]
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[[Category: Alternative splicing]]
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[[Category: Aspartyl protease]]
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[[Category: Bace]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:57:36 2008''

Revision as of 12:57, 10 December 2008

Template:STRUCTURE 2ze1

X-ray structure of Bace-1 in complex with compound 6g

Template:ABSTRACT PUBMED 18162398

About this Structure

2ZE1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets., Cole DC, Stock JR, Chopra R, Cowling R, Ellingboe JW, Fan KY, Harrison BL, Hu Y, Jacobsen S, Jennings LD, Jin G, Lohse PA, Malamas MS, Manas ES, Moore WJ, O'Donnell MM, Olland AM, Robichaud AJ, Svenson K, Wu J, Wagner E, Bard J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1063-6. Epub 2007 Dec 10. PMID:18162398

Page seeded by OCA on Wed Dec 10 14:57:36 2008

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