2vkm

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(New page: '''Unreleased structure''' The entry 2vkm is ON HOLD Authors: Hong, L., Tang, J., Ghosh, A.K. Description: Crystal structure of GRL-8234 bound to BACE (Beta-secretase) ''Page seeded ...)
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'''Unreleased structure'''
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[[Image:2vkm.jpg|left|200px]]
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The entry 2vkm is ON HOLD
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{{STRUCTURE_2vkm| PDB=2vkm | SCENE= }}
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Authors: Hong, L., Tang, J., Ghosh, A.K.
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===CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)===
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Description: Crystal structure of GRL-8234 bound to BACE (Beta-secretase)
 
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{{ABSTRACT_PUBMED_18180160}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 08:52:45 2008''
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==About this Structure==
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2VKM is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKM OCA].
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==Reference==
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Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation., Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18180160 18180160]
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[[Category: Homo sapiens]]
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[[Category: Ghosh, A K.]]
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[[Category: Hong, L.]]
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[[Category: Tang, J.]]
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[[Category: A-beta]]
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[[Category: Alternative splicing]]
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[[Category: Alzheimer]]
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[[Category: App]]
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[[Category: Aspartic protease]]
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[[Category: Aspartyl protease]]
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[[Category: Bace]]
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[[Category: Beta secretase]]
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[[Category: Drug design]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Memapsin]]
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[[Category: Membrane]]
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[[Category: Protease]]
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[[Category: Transmembrane]]
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[[Category: X- ray]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:20:52 2008''

Revision as of 11:21, 17 December 2008

Image:2vkm.jpg

Template:STRUCTURE 2vkm

CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)

Template:ABSTRACT PUBMED 18180160

About this Structure

2VKM is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation., Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:18180160

Page seeded by OCA on Wed Dec 17 13:20:52 2008

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