3dm6

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3dm6.jpg|left|200px]]
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The entry 3dm6 is ON HOLD until Paper Publication
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{{STRUCTURE_3dm6| PDB=3dm6 | SCENE= }}
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Authors: Back, M., Nyhlen, J., Kvarnstrom, I., Appelgren, S., Borkakoti, N., Jansson, K., Lindberg, J.D., Nystrom, S., Rosenquist, A., Hallberg, A., Samuelsson, B.
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===Beta-secretase 1 complexed with statine-based inhibitor===
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Description: Beta-secretase 1 complexed with statine-based inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 12:15:03 2008''
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{{ABSTRACT_PUBMED_18842420}}
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==About this Structure==
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3DM6 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DM6 OCA].
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==Reference==
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Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues., Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B, Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18842420 18842420]
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Borkakoti, N.]]
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[[Category: Lindberg, J.]]
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[[Category: Nystrom, S.]]
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[[Category: Alternative splicing]]
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[[Category: Aspartyl protease]]
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[[Category: Bace]]
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[[Category: Beta-secretase]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Membrane]]
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[[Category: Protease]]
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[[Category: Statine]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:43:10 2008''

Revision as of 11:43, 17 December 2008

Image:3dm6.jpg

Template:STRUCTURE 3dm6

Beta-secretase 1 complexed with statine-based inhibitor

Template:ABSTRACT PUBMED 18842420

About this Structure

3DM6 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues., Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B, Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420

Page seeded by OCA on Wed Dec 17 13:43:10 2008

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