This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox2qc8
From Proteopedia
(Difference between revisions)
(→Glutamine Synthetase: Secondary structures) |
|||
| Line 14: | Line 14: | ||
=Glutamine Synthetase: Secondary structures= | =Glutamine Synthetase: Secondary structures= | ||
| - | Glutamine synthetase is composed of 12 <scene name='Sandbox2qc8/ | + | Glutamine synthetase is composed of 12 <scene name='Sandbox2qc8/Identical_subunits/1'>TextToBeDisplayed</scene>. |
Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. <ref>Yamashita, M., et al.,Refined Atomic Model of Glutamine Synthetase at 3.5A Resolution, The Journal of Biological Chemistry, 1989, 17681-17690.</ref> | Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. <ref>Yamashita, M., et al.,Refined Atomic Model of Glutamine Synthetase at 3.5A Resolution, The Journal of Biological Chemistry, 1989, 17681-17690.</ref> | ||
| + | |||
Each subunit is composed predominantly of 12 <scene name='Sandbox2qc8/Subunit_alpha/1'>alpha helices</scene> and 12 | Each subunit is composed predominantly of 12 <scene name='Sandbox2qc8/Subunit_alpha/1'>alpha helices</scene> and 12 | ||
Revision as of 17:02, 17 December 2008
| |||||||||
| 2qc8, resolution 2.60Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||||
| Gene: | GLUL, GLNS (Homo sapiens) | ||||||||
| Activity: | Glutamate--ammonia ligase, with EC number 6.3.1.2 | ||||||||
| Related: | 2ojw | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Exercises
Click here to view .
Click here to view .
Click here to view .
Click here to view .
Glutamine Synthetase: Secondary structures
Glutamine synthetase is composed of 12 .
Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. [1]
Each subunit is composed predominantly of 12 and 12
, as well as a .
The beta sheets are arranged into two separate partial beta barrels, one of which encompasses the ligand complex.
The active site within the secondary structure can be called a "bifunnel," providing access to ATP and glutamate at opposing ends.[2]
The ligands present are Cl, Mn, Adenosine Diphosphate, and L-Methionine-S-Sulfoximine Phosphate.
