Sandbox2qc8
From Proteopedia
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(→Glutamine Synthetase: Secondary structures) |
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=Glutamine Synthetase: Secondary structures= | =Glutamine Synthetase: Secondary structures= | ||
| - | Glutamine synthetase is composed of 12 <scene name='Sandbox2qc8/Identical_subunits/1'>identical subunits</scene>. Each subunit is composed of 15 <scene name='Sandbox2qc8/15_alpha_helices/1'> | + | Glutamine synthetase is composed of 12 <scene name='Sandbox2qc8/Identical_subunits/1'>identical subunits</scene>. Each subunit is composed of 15 <scene name='Sandbox2qc8/15_alpha_helices/1'>alpha helices</scene> and 12 |
<scene name='Sandbox2qc8/Subunit_beta/1'>beta sheets</scene>, as well as a <scene name='Sandbox2qc8/Subunit_ligand/1'>ligand complex</scene>. | <scene name='Sandbox2qc8/Subunit_beta/1'>beta sheets</scene>, as well as a <scene name='Sandbox2qc8/Subunit_ligand/1'>ligand complex</scene>. | ||
Revision as of 17:33, 17 December 2008
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| 2qc8, resolution 2.60Å () | |||||||||
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| Ligands: | , , , | ||||||||
| Gene: | GLUL, GLNS (Homo sapiens) | ||||||||
| Activity: | Glutamate--ammonia ligase, with EC number 6.3.1.2 | ||||||||
| Related: | 2ojw | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Exercises
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Glutamine Synthetase: Secondary structures
Glutamine synthetase is composed of 12 . Each subunit is composed of 15 and 12 , as well as a .
Each subunit has an exposed NH2 terminus and buried COOH terminus as part of a helical thong. [1]
The beta sheets are arranged into two separate partial beta barrels, one of which encompasses the ligand complex.
The active site within the secondary structure can be called a "bifunnel," providing access to ATP and glutamate at opposing ends.[2]
The ligands present are Cl, Mn, Adenosine Diphosphate, and L-Methionine-S-Sulfoximine Phosphate.
