This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3cas
From Proteopedia
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3cas. | + | [[Image:3cas.png|left|200px]] |
<!-- | <!-- | ||
| Line 12: | Line 12: | ||
===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione=== | ===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19075558}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19075558 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_19075558}} | ||
==About this Structure== | ==About this Structure== | ||
3CAS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAS OCA]. | 3CAS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAS OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition., Faucher F, Cantin L, Luu-The V, Labrie F, Breton R, Biochemistry. 2008 Dec 23;47(51):13537-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19075558 19075558] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Breton, R]] | [[Category: Breton, R]] | ||
| Line 36: | Line 45: | ||
[[Category: Substrate inhibition]] | [[Category: Substrate inhibition]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:01:04 2008'' |
Revision as of 09:01, 24 December 2008
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione
Template:ABSTRACT PUBMED 19075558
About this Structure
3CAS is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition., Faucher F, Cantin L, Luu-The V, Labrie F, Breton R, Biochemistry. 2008 Dec 23;47(51):13537-46. PMID:19075558
Page seeded by OCA on Wed Dec 24 11:01:04 2008
Categories: Homo sapiens | Breton, R | Cantin, L | Faucher, F | 5b-red | 5b-reductase | 5beta-reductase | Akr | Akr1d1 | Aldo-keto reductase | Androstenedione | Bile acid catabolism | Cytoplasm | Disease mutation | Lipid metabolism | Nadp | Nadph | Oxidoreductase | Steroid metabolism | Substrate inhibition
