3bsc

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(New page: '''Unreleased structure''' The entry 3bsc is ON HOLD until Dec 23 2009 Authors: Zhao, Q., Showalter, R.E., Han, Q., Kissinger, C.R. Description: Crystal Structure of HCV NS5B Polymeras...)
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'''Unreleased structure'''
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[[Image:3bsc.jpg|left|200px]]
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The entry 3bsc is ON HOLD until Dec 23 2009
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{{STRUCTURE_3bsc| PDB=3bsc | SCENE= }}
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Authors: Zhao, Q., Showalter, R.E., Han, Q., Kissinger, C.R.
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===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor===
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Description: Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor
 
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{{ABSTRACT_PUBMED_18242088}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:27:53 2008''
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==About this Structure==
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3BSC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSC OCA].
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==Reference==
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Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine., Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18242088 18242088]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Viruses]]
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[[Category: Han, Q.]]
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[[Category: Kissinger, C R.]]
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[[Category: Showalter, R E.]]
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[[Category: Zhao, Q.]]
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[[Category: Protein-ligand complex]]
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[[Category: Rna replication]]
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[[Category: Rna-binding]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Viral nucleoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:20 2008''

Revision as of 09:29, 24 December 2008

Image:3bsc.jpg

Template:STRUCTURE 3bsc

Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor

Template:ABSTRACT PUBMED 18242088

About this Structure

3BSC is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine., Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088

Page seeded by OCA on Wed Dec 24 11:29:20 2008

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