3ens
From Proteopedia
Line 1: | Line 1: | ||
- | + | {{Seed}} | |
+ | [[Image:3ens.jpg|left|200px]] | ||
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3ens", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
+ | or leave the SCENE parameter empty for the default display. | ||
+ | --> | ||
+ | {{STRUCTURE_3ens| PDB=3ens | SCENE= }} | ||
- | + | ===Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate=== | |
- | Description: Crystal structure of human FXA in complex with (S,E)-methyl 3-(3-chloro-1h-indol-7-ylamino)-2-cyano-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-ylamino)acrylate | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
+ | The line below this paragraph, {{ABSTRACT_PUBMED_18998662}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 18998662 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_18998662}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | 3ENS is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENS OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18998662 18998662] | ||
+ | [[Category: Coagulation factor Xa]] | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Klei, H E.]] | ||
+ | [[Category: Blood clotting]] | ||
+ | [[Category: Blood coagulation factor]] | ||
+ | [[Category: Calcium]] | ||
+ | [[Category: Cleavage on pair of basic residue]] | ||
+ | [[Category: Egf-like domain]] | ||
+ | [[Category: Epidermal growth factor like domain]] | ||
+ | [[Category: Gamma-carboxyglutamic acid]] | ||
+ | [[Category: Glycoprotein]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Hydroxylation]] | ||
+ | [[Category: Polymorphism]] | ||
+ | [[Category: Serine protease]] | ||
+ | [[Category: Zymogen]] | ||
+ | |||
+ | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:33:40 2008'' |
Revision as of 08:33, 31 December 2008
Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
Template:ABSTRACT PUBMED 18998662
About this Structure
3ENS is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:18998662
Page seeded by OCA on Wed Dec 31 10:33:40 2008
Categories: Coagulation factor Xa | Homo sapiens | Klei, H E. | Blood clotting | Blood coagulation factor | Calcium | Cleavage on pair of basic residue | Egf-like domain | Epidermal growth factor like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Polymorphism | Serine protease | Zymogen