3fde

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==Reference==
==Reference==
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UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications., Hashimoto H, Horton JR, Zhang X, Cheng X, Epigenetics. 2009 Jan 10;4(1). PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19077538 19077538]
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<ref group="xtra">PMID:19077538</ref><ref group="xtra">PMID:18772888</ref><references group="xtra"/>
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The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix., Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X, Nature. 2008 Oct 9;455(7214):826-9. Epub 2008 Sep 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18772888 18772888]
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[[Category: Mus musculus]]
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[[Category: Cheng, X.]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 7 09:44:02 2009''
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Revision as of 07:17, 21 January 2009

Image:3fde.png

Template:STRUCTURE 3fde

Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution

Template:ABSTRACT PUBMED 19077538

About this Structure

3FDE is a 6 chains structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Hashimoto H, Horton JR, Zhang X, Cheng X. UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics. 2009 Jan 10;4(1). PMID:19077538
  • Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature. 2008 Oct 9;455(7214):826-9. Epub 2008 Sep 3. PMID:18772888 doi:10.1038/nature07280

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