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3fcu

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3fcu.jpg|left|200px]]
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The entry 3fcu is ON HOLD
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{{STRUCTURE_3fcu| PDB=3fcu | SCENE= }}
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Authors: Zhu, J., Luo, B.-H., Xiao, T., Zhang, C., Nishida, N., Springer, T.A.
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===Structure of headpiece of integrin aIIBb3 in open conformation===
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Description: structure of integrin aIIBb3
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:42 2008''
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The line below this paragraph, {{ABSTRACT_PUBMED_19111664}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19111664 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19111664}}
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==Disease==
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Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]], Thrombocytopenia, neonatal alloimmune OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]]
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==About this Structure==
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3FCU is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCU OCA].
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==Reference==
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<ref group="xtra">PMID:19111664</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Luo, B H.]]
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[[Category: Nishida, N.]]
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[[Category: Springer, T A.]]
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[[Category: Xiao, T.]]
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[[Category: Zhang, C.]]
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[[Category: Zhu, J.]]
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[[Category: Allostery]]
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[[Category: Alternative splicing]]
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[[Category: Cell adhesion]]
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[[Category: Cell adhesion/blood clotting complex]]
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[[Category: Cell adhesion/immune system complex]]
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[[Category: Crystal structure]]
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[[Category: Disease mutation]]
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[[Category: Fibrinogen binding]]
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[[Category: Glycoprotein]]
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[[Category: Host-virus interaction]]
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[[Category: Integrin]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Platelet integrin alphaiibbeta3]]
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[[Category: Polymorphism]]
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[[Category: Receptor]]
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[[Category: Therapeutic antagonism]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:49:26 2009''

Revision as of 08:49, 21 January 2009

Image:3fcu.jpg

Template:STRUCTURE 3fcu

Contents

Structure of headpiece of integrin aIIBb3 in open conformation

Template:ABSTRACT PUBMED 19111664

Disease

Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[607759], Thrombocytopenia, neonatal alloimmune OMIM:[607759]

About this Structure

3FCU is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018

Page seeded by OCA on Wed Jan 21 10:49:26 2009

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