3faa
From Proteopedia
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| + | [[Image:3faa.jpg|left|200px]] | ||
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| + | {{STRUCTURE_3faa| PDB=3faa | SCENE= }} | ||
| - | + | ===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor=== | |
| - | Description: Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19135364}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19135364 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19135364}} | ||
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| + | ==Disease== | ||
| + | Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]] | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3FAA is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19135364</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Receptor protein serine/threonine kinase]] | ||
| + | [[Category: Boriack-Sjodin, P A.]] | ||
| + | [[Category: Fitch, C.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Craniosynostosis]] | ||
| + | [[Category: Disease mutation]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Manganese]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Protein-inhibitor complex]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Structure-based drug design]] | ||
| + | [[Category: Tgfbeta]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transmembrane]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:55:14 2009'' | ||
Revision as of 07:55, 28 January 2009
Contents |
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Template:ABSTRACT PUBMED 19135364
Disease
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this Structure
3FAA is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119
Page seeded by OCA on Wed Jan 28 09:55:14 2009
Categories: Homo sapiens | Receptor protein serine/threonine kinase | Boriack-Sjodin, P A. | Fitch, C. | Atp-binding | Craniosynostosis | Disease mutation | Glycoprotein | Kinase | Magnesium | Manganese | Membrane | Metal-binding | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein-inhibitor complex | Receptor | Serine/threonine-protein kinase | Structure-based drug design | Tgfbeta | Transferase | Transmembrane
