3dox
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | 3DOX is a | + | 3DOX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2_group_m_subtype_b) Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOX OCA]. |
==Reference== | ==Reference== | ||
- | + | X-ray structure of HIV-1 protease in situ product complex., Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV, Proteins. 2008 Aug 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18704947 18704947] | |
+ | |||
+ | 1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR., Pillai B, Kannan KK, Hosur MV, Proteins. 2001 Apr 1;43(1):57-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11170214 11170214] | ||
+ | |||
+ | Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex., Kumar M, Prashar V, Mahale S, Hosur MV, Biochem J. 2005 Jul 15;389(Pt 2):365-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15794743 15794743] | ||
+ | |||
+ | Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction., Pillai B, Kannan KK, Bhat SV, Hosur MV, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):594-6. Epub 2004, Feb 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14993705 14993705] | ||
+ | |||
+ | Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates., Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV, Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. Epub 2006 Nov 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17116869 17116869] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
- | [[Category: | + | [[Category: Protein complex]] |
- | [[Category: | + | [[Category: Pdbx_ordinal=, <PDBx:audit_author.]] |
- | + | ||
- | + | ||
- | + | ||
[[Category: Aid]] | [[Category: Aid]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
Line 66: | Line 71: | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 20:12:25 2009'' |
Revision as of 05:13, 6 February 2009
X-ray structure of HIV-1 protease in situ product complex
Template:ABSTRACT PUBMED 18704947
About this Structure
3DOX is a Protein complex structure of sequences from Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b). Full crystallographic information is available from OCA.
Reference
X-ray structure of HIV-1 protease in situ product complex., Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV, Proteins. 2008 Aug 14. PMID:18704947
1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR., Pillai B, Kannan KK, Hosur MV, Proteins. 2001 Apr 1;43(1):57-64. PMID:11170214
Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex., Kumar M, Prashar V, Mahale S, Hosur MV, Biochem J. 2005 Jul 15;389(Pt 2):365-71. PMID:15794743
Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction., Pillai B, Kannan KK, Bhat SV, Hosur MV, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):594-6. Epub 2004, Feb 25. PMID:14993705
Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates., Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV, Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. Epub 2006 Nov 20. PMID:17116869[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
Page seeded by OCA on Wed Feb 4 20:12:25 2009
Categories: HIV-1 retropepsin | Protein complex | Aid | Aspartyl protease | Capsid maturation | Capsid protein | Catalysis | Cytoplasm | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv-1 protease | Host-virus interaction | Hydrolase | Inhibitor | Lipoprotein | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nuclease | Nucleotidyltransferase | Nucleus | Phosphoprotein | Protease | Reaction intermediate | Ribosomal frameshifting | Rna-binding | Rna-directed dna polymerase | Transferase | Transition state | Viral nucleoprotein | Virion | X-ray crystallography | Zinc | Zinc-finger