3co9

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(New page: '''Unreleased structure''' The entry 3co9 is ON HOLD until Paper Publication Authors: Han, Q., Showalter, R.E., Zhao, Q., Kissinger, C.R. Description: Crystal structure of HCV NS5B pol...)
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'''Unreleased structure'''
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[[Image:3co9.jpg|left|200px]]
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The entry 3co9 is ON HOLD until Paper Publication
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{{STRUCTURE_3co9| PDB=3co9 | SCENE= }}
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Authors: Han, Q., Showalter, R.E., Zhao, Q., Kissinger, C.R.
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===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===
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Description: Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
 
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{{ABSTRACT_PUBMED_18487044}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:33:03 2008''
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==About this Structure==
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3CO9 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CO9 OCA].
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==Reference==
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<ref group="xtra">PMID:18487044</ref><references group="xtra"/>
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Viruses]]
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[[Category: Han, Q.]]
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[[Category: Kissinger, C R.]]
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[[Category: Showalter, R E.]]
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[[Category: Zhao, Q.]]
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[[Category: Antiviral]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Protein-ligand complex]]
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[[Category: Ribonucleoprotein]]
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[[Category: Rna replication]]
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[[Category: Rna-binding]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:39:47 2009''

Revision as of 10:39, 11 February 2009

Template:STRUCTURE 3co9

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18487044

About this Structure

3CO9 is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  • Ruebsam F, Webber SE, Tran MT, Tran CV, Murphy DE, Zhao J, Dragovich PS, Kim SH, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3616-21. Epub 2008 May 1. PMID:18487044 doi:10.1016/j.bmcl.2008.04.066

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