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3faa

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==About this Structure==
==About this Structure==
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3FAA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].
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3FAA is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].
==Reference==
==Reference==
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2-Aminoimidazoles inhibitors of TGF-beta receptor 1., Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC, Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19135364 19135364]
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<ref group="xtra">PMID:19135364</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Receptor protein serine/threonine kinase]]
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[[Category: Single protein]]
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[[Category: Boriack-Sjodin, P A.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Fitch, C.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Craniosynostosis]]
[[Category: Craniosynostosis]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 20:12:09 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 15 08:48:13 2009''

Revision as of 06:48, 15 February 2009

Image:3faa.png

Template:STRUCTURE 3faa

Contents

Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor

Template:ABSTRACT PUBMED 19135364

Disease

Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this Structure

3FAA is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119

Page seeded by OCA on Sun Feb 15 08:48:13 2009

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