2uxx

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==About this Structure==
==About this Structure==
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2UXX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA].
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2UXX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA].
==Reference==
==Reference==
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Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine., Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H, Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17569509 17569509]
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<ref group="xtra">PMID:17569509</ref><ref group="xtra">PMID:16885027</ref><references group="xtra"/>
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Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase., Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H, Mol Cell. 2006 Aug 4;23(3):377-87. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16885027 16885027]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Cole, P A.]]
[[Category: Cole, P A.]]
[[Category: Culhane, J C.]]
[[Category: Culhane, J C.]]
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[[Category: Tranylcypromine]]
[[Category: Tranylcypromine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:37:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:22:11 2009''

Revision as of 08:22, 16 February 2009

Image:2uxx.png

Template:STRUCTURE 2uxx

HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT

Template:ABSTRACT PUBMED 17569509

About this Structure

2UXX is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
  • Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012

Page seeded by OCA on Mon Feb 16 10:22:11 2009

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