2w17

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==About this Structure==
==About this Structure==
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2W17 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W17 OCA].
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2W17 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W17 OCA].
==Reference==
==Reference==
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The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing., Jones CD, Andrews DM, Barker AJ, Blades K, Daunt P, East S, Geh C, Graham MA, Johnson KM, Loddick SA, McFarland HM, McGregor A, Moss L, Rudge DA, Simpson PB, Swain ML, Tam KY, Tucker JA, Walker M, Bioorg Med Chem Lett. 2008 Dec 15;18(24):6369-73. Epub 2008 Oct 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18996007 18996007]
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<ref group="xtra">PMID:18996007</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Andrews, D M.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Barker, A J.]]
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[[Category: Blades, K.]]
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[[Category: Brassington, C.]]
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[[Category: Daunt, P.]]
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[[Category: East, S.]]
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[[Category: Geh, C.]]
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[[Category: Graham, M A.]]
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[[Category: Haye, H.]]
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[[Category: Johnson, K M.]]
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[[Category: Jones, C D.]]
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[[Category: Loddick, S A.]]
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[[Category: Mccall, E.]]
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[[Category: Mcfarland, H M.]]
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[[Category: Mcgregor, A.]]
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[[Category: Moss, L.]]
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[[Category: Rudge, D A.]]
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[[Category: Simpson, P B.]]
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[[Category: Swain, M L.]]
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[[Category: Tam, K Y.]]
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[[Category: Tucker, J A.]]
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[[Category: Walker, M.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 20:33:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:47:43 2009''

Revision as of 09:47, 16 February 2009

Template:STRUCTURE 2w17

CDK2 IN COMPLEX WITH THE IMIDAZOLE PYRIMIDINE AMIDE, COMPOUND (S)-8B

Template:ABSTRACT PUBMED 18996007

About this Structure

2W17 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jones CD, Andrews DM, Barker AJ, Blades K, Daunt P, East S, Geh C, Graham MA, Johnson KM, Loddick SA, McFarland HM, McGregor A, Moss L, Rudge DA, Simpson PB, Swain ML, Tam KY, Tucker JA, Walker M. The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6369-73. Epub 2008 Oct 25. PMID:18996007 doi:10.1016/j.bmcl.2008.10.102

Page seeded by OCA on Mon Feb 16 11:47:43 2009

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