2qe5

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==About this Structure==
==About this Structure==
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2QE5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QE5 OCA].
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2QE5 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QE5 OCA].
==Reference==
==Reference==
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Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase., Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J, J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17402724 17402724]
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<ref group="xtra">PMID:17402724</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Single protein]]
 
[[Category: Bard, J.]]
[[Category: Bard, J.]]
[[Category: Chopra, R.]]
[[Category: Chopra, R.]]
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[[Category: Transferase polymerase]]
[[Category: Transferase polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:31:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:19:49 2009''

Revision as of 10:19, 16 February 2009

Template:STRUCTURE 2qe5

Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor

Template:ABSTRACT PUBMED 17402724

About this Structure

2QE5 is a 4 chains structure of sequences from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

Reference

  • Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase. J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:17402724 doi:10.1021/jm061428x

Page seeded by OCA on Mon Feb 16 12:19:49 2009

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