1xm5

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spinqualitylabelsall models 1xm5, resolution 2.7Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054

Overview

The three-dimensional crystallographic structure of the ybeY protein from, Escherichia coli (SwissProt entry P77385) is reported at 2.7 A resolution., YbeY is a hypothetical protein that belongs to the UPF0054 family. The, structure reveals that the protein binds a metal ion in a tetrahedral, geometry. Three coordination sites are provided by histidine residues, while the fourth might be a water molecule that is not seen in the, diffraction map because of its relatively low resolution. X-ray, fluorescence analysis of the purified protein suggests that the metal is a, nickel ion. The structure of ybeY and its sequence similarity to a number, of predicted metal-dependent hydrolases provides a functional assignment, for this protein family. The figures and tables of this paper were, prepared using semi-automated tools, termed the Autopublish server, developed by the New York Structural GenomiX Research Consortium, with the, goal of facilitating the rapid publication of crystallographic structures, that emanate from worldwide Structural Genomics efforts, including the, NIH-funded Protein Structure Initiative.

About this Structure

1XM5 is a Single protein structure of sequence from Escherichia coli with NI as ligand. Full crystallographic information is available from OCA.

Reference

The ybeY protein from Escherichia coli is a metalloprotein., Zhan C, Fedorov EV, Shi W, Ramagopal UA, Thirumuruhan R, Manjasetty BA, Almo SC, Fiser A, Chance MR, Fedorov AA, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2005 Nov 1;61(Pt, 11):959-63. Epub 2005 Oct 20. PMID:16511207

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