2flb

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==About this Structure==
==About this Structure==
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2FLB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLB OCA].
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2FLB is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLB OCA].
==Reference==
==Reference==
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Discovery of novel hydroxy pyrazole based factor IXa inhibitor., Vijaykumar D, Sprengeler PA, Shaghafi M, Spencer JR, Katz BA, Yu C, Rai R, Young WB, Schultz B, Janc J, Bioorg Med Chem Lett. 2006 May 15;16(10):2796-9. Epub 2006 Feb 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16487703 16487703]
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<ref group="xtra">PMID:16487703</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Katz, B A.]]
[[Category: Katz, B A.]]
[[Category: Active site-directed]]
[[Category: Active site-directed]]
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[[Category: Short hydrogen bond-mediated]]
[[Category: Short hydrogen bond-mediated]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:55:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:06:23 2009''

Revision as of 13:06, 16 February 2009

Template:STRUCTURE 2flb

Contents

Discovery of a Novel Hydroxy Pyrazole Based Factor IXa Inhibitor

Template:ABSTRACT PUBMED 16487703

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

2FLB is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Vijaykumar D, Sprengeler PA, Shaghafi M, Spencer JR, Katz BA, Yu C, Rai R, Young WB, Schultz B, Janc J. Discovery of novel hydroxy pyrazole based factor IXa inhibitor. Bioorg Med Chem Lett. 2006 May 15;16(10):2796-9. Epub 2006 Feb 17. PMID:16487703 doi:10.1016/j.bmcl.2006.01.123

Page seeded by OCA on Mon Feb 16 15:06:23 2009

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