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3ciz

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==About this Structure==
==About this Structure==
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3CIZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIZ OCA].
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3CIZ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIZ OCA].
==Reference==
==Reference==
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Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors., Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T, Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18400495 18400495]
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<ref group="xtra">PMID:18400495</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Single protein]]
 
[[Category: Hendle, j.]]
[[Category: Hendle, j.]]
[[Category: Acetylation]]
[[Category: Acetylation]]
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[[Category: Zinc]]
[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:09:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:06:53 2009''

Revision as of 13:06, 16 February 2009

Image:3ciz.png

Template:STRUCTURE 3ciz

Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments

Template:ABSTRACT PUBMED 18400495

About this Structure

3CIZ is a 2 chains structure of sequences from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

Reference

  • Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T. Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:18400495 doi:http://dx.doi.org/10.1016/j.bmcl.2008.03.056

Page seeded by OCA on Mon Feb 16 15:06:53 2009

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